Core Faculty

The Institute for Genomics & Systems Biology (IGSB) will house 9 to 10 core faculty members in genomics and computational biology at the University of Chicago and several scientists at Argonne National Laboratory. Three Core Faculty have already been recruited since the Institute was established in July 2006.

Each Core Faculty has a primary appointment in a University of Chicago Department and membership in IGSB as a Core Faculty. This facilitates collaboration in a rich mix of scientific areas and offers partnering departments the opportunity to build their genomics and systems biology expertise.

Jones

Rich Jones, Assistant Professor, Ben May Institute for Cancer Research, The University of Chicago
Jones was jointly appointed Assistant Professor of the IGSB and the Ben May Institute for Cancer Research in September 2006. As a postdoc at Harvard, Jones pioneered the use of protein microarrays to study complex molecular signaling networks involved in human cancers and other diseases. His new IGSB laboratory utilizes advanced proteomics and genomics technologies to better understand the complex signal transduction mechanisms that result in cancer, diabetes, and other human disease. An understanding of these processes at the molecular level should enable the identification of many new therapeutic targets. [homepage]

Rzhetsky

Andrey Rzhetsky, Professor, Department of Medicine, The University of Chicago; Senior Fellow, Computation Institute
Rzhetsky was the Professor of Biomedical Informatics and Biology at Columbia University until he joined the faculty at the University of Chicago and Argonne National Laboratory in 2007. Dr. Rzhetsky's interest is in (asymptotic) understanding how phenotypes, such as human healthy diversity and maladies, are implemented at the level of genes and networks of interacting molecules. To harvest as much information about known molecular interactions as possible, his group runs a large-scale text-mining effort aiming at analysis of a vast corpus of biomedical publications. Currently they can extract from text automatically about 500 distinct flavors of relations among biomedical entities (such as bind, activate, merystilate, and transport). [homepage]

White

Kevin White, Professor, James and Karen Frank Family Professor of Human Genetics, and Professor of Ecology & Evolution, The University of Chicago; Director, Institute for Genomics & Systems Biology, The University of Chicago & Argonne Natational Laboratory; Pritzker Fellow, University of Chicago Pritzker School of Medicine; Investigator, Chicago Biomedical Consortium
White is a pioneer in combining experimental and computational techniques to understand the networks of factors that control biological systems during development and evolution. He has developed novel integrted systems biology approaches for studying complex diseases and identifying new diagnostic biomarkers for a variety of cancer types. [homepage]

Dion

Dionysios A. Antonopoulos, Assistant Professor, Department of Medicine, The University of Chicago
Antonopoulos joined the IGSB and Biosciences Divisions at Argonne National Laboratory in June 2008 and holds a joint appointment in the Department of Medicine, Section of Gastroenterology, at the University. His graduate work at the University of Illinois at Urbana-Champaign on the genomics of cellulose-degrading microorganisms led to an interest in the ability of microbial communities to mediate complex substrate conversions. This led to postdoctoral positions studying the microbial ecology of soil as well as the microbial community of the mammalian gastrointestinal tract in relation to antibiotic administration. His present research is focused on soil metagenomics using next-generation DNA sequencing technologies, as well as applying the same analytical tools to understanding a variety of diseases of the GI tract. He works closely with members of the High-Throughput Genome Analysis Core as well as the Mathematics and Computer Science Division at Argonne.