News Archive

2013

Hormones and Microbes Interact to Modify Autoimmune Disease Progression

Hormones and Microbes Interact to Modify Autoimmune Disease Progression

IGSB/CBC Postdoctoral Fellow Aly Khan co-authored a study on a previously unknown interaction between gut bacteria and gender bias in autoimmune diseases. The study proposes a novel two-signal model, in which hormones and microbes together influence the incidence and severity of autoimmune diseases. The results were published in Cell Immunity and are highlighted in a featured article in the issue.

Chicago Biomedical Consortium announces 2013 spring HTS awards

Chicago Biomedical Consortium announces 2013 spring HTS awards

Congratulations to Ernst Lengyel, Hillary Kenny, Christopher Gomez, Marsha Rosner and Kay MacLeod, who have been awarded grants from the Chicago Biomedical Consortium in support of high throughput screening projects.  They will be working with the Cellular Screening Center to develop their small molecule screens for drug discovery.

IGSB welcomes the 2013 CCSB summer REU students

IGSB welcomes the 2013 CCSB summer REU students

The 10-week Chicago Center for Systems Biology summer REU program kicked off this past Tuesday. Students will work in the labs of Kevin White, Michael Rust, Richard Carthew, Rick Morimoto and Ilya Ruvinsky, on projects ranging from circadian rhythms in cyanobacteria to Drosophila development.

Bionimbus Protected Data Cloud eliminates need for massive storage infrastructure

Bionimbus Protected Data Cloud eliminates need for massive storage infrastructure

Bionimbus, an advanced cloud-based computing environment, helped Megan McNerney discover tumor suppressor gene, CUX1, is frequently inactivated in acute myeloid leukemia. The principal investigator for Bionimbus is Robert Grossman.

Gifts to boost University of Chicago as hub for biomedical ‘big data’

Gifts to boost University of Chicago as hub for biomedical ‘big data’

Two major gifts will build momentum behind the University of Chicago’s leadership in biomedical computation by assembling experts in the field and furnishing them with the tools to use “big data” to understand and treat disease.  Kevin White and Robert Grossman will lead the Pancreatic Cancer Genomic Medicine Initiative, which aims to improve care for patients with this disease using genomic and physiological data.

Immunity, inflammation and natural selection

Immunity, inflammation and natural selection

Barbara Stranger and colleagues take a systems approach, integrating GWAS, eQTL and protein interaction data, to demonstrate that loci associated with inflammatory disease susceptibility are enriched for genomic signatures of recent evolutionary selection.  Their analyses suggest that natural selection for pathogen-defense mechanisms through human evolution may underlie modern susceptibility to inflammatory diseases.

Robert Grossman named a Federal 100 Award winner

Robert Grossman named a Federal 100 Award winner

The annual list, published by Federal Computer Week, recognizes government, industry and academic leaders who have played pivotal roles in the federal government IT community.

CBC announces a high throughput screening award

CBC announces a high throughput screening award

In response to the community-wide interest in High Throughput Screening, the Chicago Biomedical Consortium is offering a 1:1 HTS Matching Grant Program to help fund innovative small molecule discovery. The intent of this program is to support pilot projects involving bio medically-relevant targets using a HTS facility located at one of the CBC universities, including the IGSB’s Cellular Screening Center.

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